Thrombotic thrombocytopenic purpura ttp is the most extensive and dangerous intravascular platelet clumping disorder. Moschcowitz was the first to inform multiple hyaline thrombi as the primordial finding of a partial autopsy case. Immune or idiopathic thrombocytopenic purpura itp in childhood. Purpura results from the extravasation of blood cells into the skin andor mucous membranes giving rise to small purple coloured areas that do not disappear under pressure. Assessment of uk practice for management of acute childhood idiopathic thrombocytopenic purpura against. Protocolo clinico e diretrizes terapeuticas portaria sasms n. Purpura trombocitopenica autoinmune caso clinico y revision. Purpura trombocitopenica trombotica symptoms, diagnosis and.
The etiopathogenic mechanisms may result from abnormalities in any of the three components of hemostasis. Purpura trombotica trombocitopenica medicina clinica. Protocolo clinico e diretrizes terapeuticas purpura. Purpura trombocitopenica inmune idiopatica en ninos.
Purpura is a disease in which there is leakage of blood out of the blood vessels in the skin or mucosa, causing the presence of painless purplish spots, called petechiae small and large number stains or ecchymoses larger patches. It can produced in health people, but in children has been associated to viral infection, or bacterial infection. Esta enfermedad afecta a varones y a mujeres por igual. Trombocitopenia inmune primaria pediatria integral. Grading of hemorrhage in children with idiopathic thrombocytopenic purpura. Diagnosis and treatment of immune thrombocytopenic purpura wilson ruiz gil1,a. Trombocitopenia inmunitaria sintomas y causas mayo clinic. Thrombotic thrombocitopenic purpura is a rare disease with a morphological expression featured of many microthrombi in the terminal arterioles of several vital structures. Trombocitopenia inmunitaria mayo clinic mayo clinic. The group with 15 years was the largest with 335757. Trombocitopenia inmunitaria diagnostico y tratamiento mayo clinic. For more than a halfcentury after its initial recognition, mortality was near 100% and the etiology totally obscure. Purpura trombotica trombocitopenica y sindrome hemolitico uremico.
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